Fact: The causes of Dupuytren’s disease and arthritis are different. The contracture of the fingers associated with Dupuytren’s disease is caused by a thickening of the fibrous tissue that lies just below the skin of the palm and fingers. These tissues form rope-like cords that mechanically pull the finger downward. In arthritis, decreased mobility is caused by inflammation of the joint tissues or changes in the bones near the joints.

Fact: Dupuytren’s disease has been reported in a small number of people who have had hand injuries, infections or surgeries. However, the cause-effect relationship between Dupuytren’s disease and a previous hand injury is unclear. From a clinical perspective, it is difficult to determine if the injury accelerated the development of an already existing case of Dupuytren’s disease, or if the injury itself caused the disease. Discuss with your doctor any hand injuries you’ve had.

Fact: There is no clinical evidence proving that other conditions, such as diabetes, cause Dupuytren’s disease. However, several conditions, including diabetes, may increase the risk that an individual will develop Dupuytren’s disease. For example, the incidence of Dupuytren’s disease among those with diabetes seems to be higher in those who are older and who have had diabetes longer. However, there is no clinical evidence proving that other conditions, such as diabetes, cause Dupuytren’s disease.

Fact: There is no cure for Dupuytren’s disease. There are nonsurgical and surgical treatments that have been shown to be effective for treating Dupuytren’s contracture. Only your doctor can tell you which treatment option may be right for you.

Fact: There is no clinical evidence that dietary factors improve signs of Dupuytren’s disease or prevent its progression.