About Dupuytren’s Disease

Dupuytren’s (pronounced “DOO puh trenz”) disease is a progressive condition that primarily affects the hand. It begins with changes in the palm — lumps may develop at the base of the finger and the skin’s appearance may change. Then, one or more fingers gradually curl downward toward the palm. This curling (called contracture) prevents the fingers from straightening. Because of this, the disease is sometimes referred to as Dupuytren’s contracture.

As the amount of contracture increases, range of motion decreases. Even when the amount of contracture is small, it can be difficult to do ordinary things — tying shoes, opening jars or putting on gloves, for example. Because Dupuytren’s disease is progressive, its impact becomes more and more noticeable and disruptive over time.

What is Dupuytren’s Disease?
Learn about the causes of Dupuytren’s disease, the parts of the hand that may be affected and who is most likely to get the disease.

Disease Progression
Learn how Dupuytren’s disease progresses, as well as factors that can influence progression and how the disease is diagnosed.

Dupuytren’s Video Series
Watch videos about various topics related to Dupuytren’s disease, including disease progression, its impact on daily activities, and when patients should seek treatment.

Myths vs. Facts
Learn some common misconceptions about Dupuytren’s disease.

Dupuytren’s Patient Brochure
See what Dupuytren’s disease looks like and read about how it progresses and how it can affect daily activities.

Glossary
Look up the definitions of frequently used Dupuytren’s-related words.